Formulasi dan Evaluasi Fisik Suspensi Topikal Ekstrak Daun Kelor (Moringa oleifera L.) dalam Pengembangan Sediaan Antijamur Herbal
DOI:
https://doi.org/10.59024/jikas.v4i3.1764Keywords:
Antifungal, Moringa Oleifera, Physical Characteristics, Stability, Topical SuspensionAbstract
Cutaneous fungal infections caused by Malassezia furfur remain a significant health concern in tropical regions, highlighting the need for safe and effective alternative therapies. Moringa oleifera L. leaves are reported to contain various secondary metabolites, including flavonoids, tannins, and saponins, which exhibit potential antifungal activity. This study aimed to develop a topical suspension formulation of Moringa oleifera leaf extract and to evaluate the effect of varying extract concentrations on the physical characteristics of the preparation. An experimental method was employed using four formulations: F0 as the control, and F1, F2, and F3 containing 9%, 10%, and 11% extract, respectively. Evaluation parameters included organoleptic properties, homogeneity, pH, viscosity, and adhesiveness, as well as stability testing using a cycling test method for 12 days. The results demonstrated that all formulations exhibited good organoleptic characteristics, homogeneity, and viscosity. The pH values remained within the acceptable range for skin preparations, although slight fluctuations were observed during storage. Adhesiveness also showed variations across several testing cycles. Overall, the formulations met acceptable physical quality criteria and demonstrated potential for further development as topical suspensions; however, formulation optimization is still required to enhance stability during storage.
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