Hubungan Infeksi Helicobacter Pylori terhadap Kejadian Gastritis Aktif dan Ulkus Duodenum: Study Literature

Authors

  • Agisni Fatihaturrohmah Universitas Pendidikan Indonesia
  • Ayudia Shelina Audjah Universitas Pendidikan Indonesia
  • Daaniys Aqila Halwa Universitas Pendidikan Indonesia
  • Diva Tri Adzani Universitas Pendidikan Indonesia
  • Firda Aulifia Sarah Universitas Pendidikan Indonesia
  • Fitrio Danu Sudira Universitas Pendidikan Indonesia
  • Muhammad Rizwan Universitas Pendidikan Indonesia
  • Ovi Listiyani Universitas Pendidikan Indonesia
  • Popi Sopiah Universitas Pendidikan Indonesia

DOI:

https://doi.org/10.59024/jikas.v4i2.1663

Keywords:

Active Gastritis, Chronic Gastritis, Duodenal Ulcer, Helicobacter Pylori, Infection

Abstract

Helicobacter pylori infection is one of the main factors associated with the occurrence of active gastritis and duodenal ulcers. This bacterium can survive in the acidic environment of the stomach by producing the urease enzyme, allowing it to colonize the gastric mucosa and trigger an inflammatory response. This study aims to analyze the relationship between Helicobacter pylori infection and the incidence of active gastritis and duodenal ulcers. The method used was a literature review with a narrative approach of scientific articles published between 2021–2025 from the Google Scholar, OpenAlex, and Crossref databases. The results of the review indicate that Helicobacter pylori infection is significantly associated with increased gastric mucosal inflammation and a higher risk of duodenal ulcers. Early detection and eradication therapy using a combination of antibiotics and proton pump inhibitors (PPI) are effective in preventing disease progression and complications. Additional findings highlight the importance of hygiene, sanitation, and public awareness in reducing transmission rates and improving gastrointestinal health outcomes globally..

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Published

2026-05-21

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Vol. 4 No. 2 (2026): Mei : JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL

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